A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_URI::$config is deprecated

Filename: core/URI.php

Line Number: 101

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Router::$uri is deprecated

Filename: core/Router.php

Line Number: 127

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$benchmark is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$hooks is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$config is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$log is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$utf8 is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$uri is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$exceptions is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$router is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$output is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$security is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$input is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$lang is deprecated

Filename: core/Controller.php

Line Number: 75

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$load is deprecated

Filename: core/Controller.php

Line Number: 78

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$db is deprecated

Filename: core/Loader.php

Line Number: 396

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_DB_mysqli_driver::$failover is deprecated

Filename: database/DB_driver.php

Line Number: 371

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 22
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$table is deprecated

Filename: core/Loader.php

Line Number: 1283

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$form_validation is deprecated

Filename: core/Loader.php

Line Number: 1283

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Return type of CI_Session_files_driver::open($save_path, $name) should either be compatible with SessionHandlerInterface::open(string $path, string $name): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice

Filename: drivers/Session_files_driver.php

Line Number: 132

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Return type of CI_Session_files_driver::close() should either be compatible with SessionHandlerInterface::close(): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice

Filename: drivers/Session_files_driver.php

Line Number: 292

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Return type of CI_Session_files_driver::read($session_id) should either be compatible with SessionHandlerInterface::read(string $id): string|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice

Filename: drivers/Session_files_driver.php

Line Number: 166

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Return type of CI_Session_files_driver::write($session_id, $session_data) should either be compatible with SessionHandlerInterface::write(string $id, string $data): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice

Filename: drivers/Session_files_driver.php

Line Number: 235

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Return type of CI_Session_files_driver::destroy($session_id) should either be compatible with SessionHandlerInterface::destroy(string $id): bool, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice

Filename: drivers/Session_files_driver.php

Line Number: 315

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Return type of CI_Session_files_driver::gc($maxlifetime) should either be compatible with SessionHandlerInterface::gc(int $max_lifetime): int|false, or the #[\ReturnTypeWillChange] attribute should be used to temporarily suppress the notice

Filename: drivers/Session_files_driver.php

Line Number: 356

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: ini_set(): Session ini settings cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 282

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_set_cookie_params(): Session cookie parameters cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 289

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: ini_set(): Session ini settings cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 304

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: ini_set(): Session ini settings cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 314

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: ini_set(): Session ini settings cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 315

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: ini_set(): Session ini settings cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 316

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: ini_set(): Session ini settings cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 317

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: ini_set(): Session ini settings cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 375

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_set_save_handler(): Session save handler cannot be changed after headers have already been sent

Filename: Session/Session.php

Line Number: 110

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: Warning

Message: session_start(): Session cannot be started after headers have already been sent

Filename: Session/Session.php

Line Number: 143

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$session is deprecated

Filename: core/Loader.php

Line Number: 1283

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$agent is deprecated

Filename: core/Loader.php

Line Number: 1283

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 23
Function: library

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$news_model is deprecated

Filename: core/Loader.php

Line Number: 358

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 25
Function: model

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$home_model is deprecated

Filename: core/Loader.php

Line Number: 358

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 25
Function: model

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Facebook\FacebookApp implements the Serializable interface, which is deprecated. Implement __serialize() and __unserialize() instead (or in addition, if support for old PHP versions is necessary)

Filename: Facebook/FacebookApp.php

Line Number: 29

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/libraries/Facebook/php-graph-sdk-5.x/php-graph-sdk-5.x/src/Facebook/FacebookApp.php
Line: 29
Function: _error_handler

File: /home/judfadzm/public_html/healthtechseries.com/application/libraries/Facebook/php-graph-sdk-5.x/php-graph-sdk-5.x/src/Facebook/autoload.php
Line: 79
Function: require

File: /home/judfadzm/public_html/healthtechseries.com/application/libraries/Facebook/php-graph-sdk-5.x/php-graph-sdk-5.x/src/Facebook/Facebook.php
Line: 145
Function: {closure}

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 31
Function: __construct

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property News::$facebook is deprecated

Filename: controllers/News.php

Line Number: 31

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 31
Function: _error_handler

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$benchmark is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$hooks is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$config is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$log is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$utf8 is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$uri is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$exceptions is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$router is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$output is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$security is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$input is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$lang is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

A PHP Error was encountered

Severity: 8192

Message: Creation of dynamic property CI_Loader::$load is deprecated

Filename: core/Loader.php

Line Number: 931

Backtrace:

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 86
Function: view

File: /home/judfadzm/public_html/healthtechseries.com/application/controllers/News.php
Line: 16
Function: index

File: /home/judfadzm/public_html/healthtechseries.com/index.php
Line: 317
Function: require_once

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Alzheimer\'s Association Statement on Oral Semaglutide Phase 3 Topline Data Release
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Alzheimer\'s Association Statement on Oral Semaglutide Phase 3 Topline Data Release



byprnewswire
November 24,2025
(0) (567) (0)

- Results Underscore Need for Continued Research and Diverse Treatment Pipeline

CHICAGO, Nov. 24, 2025 /PRNewswire/ -- The Alzheimer\'s Association is disappointed that the evoke and evoke+ clinical trials did not demonstrate a statistically significant reduction in Alzheimer\'s disease progression. The studies tested an oral semaglutide pill for the treatment of early-stage symptomatic Alzheimer's disease.

Alzheimer's Association

"While these results are not what we had hoped for, they will contribute to our understanding of this devastating and fatal disease," said Joanne Pike, DrPH, Alzheimer's Association president and chief executive officer. "The data from every clinical trial, regardless of outcome, is vital to accelerating our understanding of this disease and helps inform the next generation of clinical trials. We remain optimistic about the future of Alzheimer's treatment and prevention, as the scientific landscape continues to diversify and expand."

The company said, "While treatment with semaglutide resulted in improvement of Alzheimer's disease-related biomarkers in both trials, this did not translate into a delay of disease progression." The evoke and evoke+ trials were large-scale, long-term international clinical trials. More than 3,800 people ages 55-85 diagnosed with mild cognitive impairment (MCI) or mild dementia due to Alzheimer's disease, (referred to as stage 3 and 4 of Alzheimer's disease), were enrolled.

"These results will help us refine our understanding of this class of drugs," said Maria C. Carrillo, Ph.D., Alzheimer's Association chief science officer and medical affairs lead. "Though this semaglutide pill did not help against Alzheimer's, the field will continue to investigate this class of drugs, as they may act differently. And, the Alzheimer's Association remains a fierce leader for this type of innovative research, and we believe it's critical to continue investigating diverse approaches to treatment and prevention."

The Alzheimer's treatment pipeline is robust and full of hope. An annual evaluation of the drug development pipeline published in Alzheimer's & Dementia: Translational Research & Clinical Interventions in early 2025, shows there are 182 active clinical trials evaluating 138 novel drugs. The Alzheimer's Association, through its "Part the Cloud" program, provides strategic funding to advance promising investigational Alzheimer's therapies into clinical trials. The treatment targets are varied, which is important given the growing consensus that effective treatment and prevention of Alzheimer's is likely to be a personalized combination of multiple interventions.

For people living with early Alzheimer's, approved treatments are available. We urge individuals to talk to their doctor about these options. Individuals can also talk to their doctor about participating in clinical trials, or visit the Alzheimer's Association's TrialMatch for more information.

The Association appreciates these topline results and looks forward to hearing a deeper dive into the data at the Clinical Trials in Alzheimer's Disease (CTAD) meeting in December.

About the Alzheimer's Association

The Alzheimer's Association is a worldwide voluntary health organization dedicated to Alzheimer's care, support and research. Our mission is to lead the way to end Alzheimer's and all other dementia — by accelerating global research, driving risk reduction and early detection, and maximizing quality care and support. Our vision is a world without Alzheimer's and all other dementia®. Visit alz.org or call 800.272.3900.

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